PND-1186 is primarily recognized for its role in the field of cancer research. It functions as a potent inhibitor of focal adhesion kinase (FAK), a protein that plays a critical role in cell adhesion, migration, and survival. By inhibiting FAK, PND-1186 disrupts signaling pathways that are often hijacked by cancer cells to promote tumor growth, metastasis, and resistance to therapy. This makes it a valuable tool in preclinical studies aimed at understanding the mechanisms of cancer progression and in the development of targeted anticancer therapies. Researchers utilize PND-1186 to explore its potential in reducing tumor invasiveness and enhancing the efficacy of existing treatments, particularly in cancers where FAK overexpression is implicated.