GW441756 is primarily used in research settings to study cellular signaling pathways, particularly those involving the TrkA receptor. It acts as a selective inhibitor of TrkA kinase activity, making it a valuable tool for investigating the role of TrkA in neuronal development, survival, and differentiation. Researchers utilize it to explore its effects on pain signaling, neurogenesis, and cancer biology, as TrkA is implicated in certain types of tumors. Additionally, GW441756 helps in understanding the mechanisms of neurotrophin signaling and its potential therapeutic applications in neurodegenerative diseases and oncology.