N-Oleoyl Dopamine (OLDA) is an endogenous lipid and member of the N-acyl dopamine family, primarily studied for its role in the endocannabinoid system, modulating pain and inflammation. It acts as an agonist for the transient receptor potential vanilloid 1 (TRPV1) channel and has affinity for cannabinoid CB1 receptors, which are involved in the sensation of pain, heat, and sensory processing. This makes OLDA a potential candidate for developing analgesic drugs, particularly for conditions involving chronic pain, inflammatory disorders, and neuropathic pain. Additionally, its interactions suggest applications in managing other sensory-related conditions. Research also explores its potential in cardiovascular health, as it may influence vasodilation and blood pressure regulation. OLDA's unique mechanism of action continues to be investigated for therapeutic use in various medical fields, including neurology and pharmacology.