Pyr3 is widely utilized in research settings for its role as a selective inhibitor of TRPC3 channels, which are involved in calcium signaling pathways. It is particularly valuable in studying the physiological and pathological functions of these channels in various cell types. Researchers employ Pyr3 to investigate its effects on conditions such as cardiac hypertrophy, neuronal signaling, and cancer progression, where TRPC3 channels play a significant role. Additionally, Pyr3 is used to explore potential therapeutic applications by modulating calcium influx in diseases linked to TRPC3 dysregulation. Its specificity makes it a critical tool in understanding calcium-dependent cellular processes and developing targeted treatments.