1,1,1-Trifluoromethanesulfonic acid 2-(1,3-dihydro-1,3-dioxo-2H-benz[f]isoindol-2-yl)ethyl ester

90%

Reagent Code: #62374
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CAS Number 128651-50-3

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blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 373.30 g/mol
Formula C₁₅H₁₀F₃NO₅S
inventory_2 Storage & Handling
Storage -20°C

description Product Description

This compound is a specialized trifluoromethanesulfonate (triflate) ester, functioning as a highly reactive electrophilic intermediate in organic synthesis. The triflate moiety serves as an excellent leaving group, facilitating nucleophilic substitutions and cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings to form carbon-carbon or carbon-heteroatom bonds. It is particularly valuable in pharmaceutical development for incorporating the 2-(1,3-dioxobenzo[f]isoindolin-2-yl)ethyl group into bioactive molecules, often as a protected form of an ethanolamine derivative. Applications extend to the synthesis of complex natural products, polymers, and other specialty chemicals where precise control over reactivity is required. Its use in medicinal chemistry aids in creating compounds with enhanced therapeutic potential, such as enzyme inhibitors or receptor agonists.

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Test Parameter Specification
Appearance White to Off-White Solid, Powder, or Crystals
Purity 89.5-100
Proton NMR Spectrum Conforms to Structure
Infrared Spectrum Conforms to Structure

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿8,622.00

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1,1,1-Trifluoromethanesulfonic acid 2-(1,3-dihydro-1,3-dioxo-2H-benz[f]isoindol-2-yl)ethyl ester
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This compound is a specialized trifluoromethanesulfonate (triflate) ester, functioning as a highly reactive electrophilic intermediate in organic synthesis. The triflate moiety serves as an excellent leaving group, facilitating nucleophilic substitutions and cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings to form carbon-carbon or carbon-heteroatom bonds. It is particularly valuable in pharmaceutical development for incorporating the 2-(1,3-dioxobenzo[f]isoindolin-2-yl)ethyl group

This compound is a specialized trifluoromethanesulfonate (triflate) ester, functioning as a highly reactive electrophilic intermediate in organic synthesis. The triflate moiety serves as an excellent leaving group, facilitating nucleophilic substitutions and cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings to form carbon-carbon or carbon-heteroatom bonds. It is particularly valuable in pharmaceutical development for incorporating the 2-(1,3-dioxobenzo[f]isoindolin-2-yl)ethyl group into bioactive molecules, often as a protected form of an ethanolamine derivative. Applications extend to the synthesis of complex natural products, polymers, and other specialty chemicals where precise control over reactivity is required. Its use in medicinal chemistry aids in creating compounds with enhanced therapeutic potential, such as enzyme inhibitors or receptor agonists.

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