1,1,1-Trifluoromethanesulfonic acid 2-(1,3-dihydro-1,3-dioxo-2H-benz[f]isoindol-2-yl)ethyl ester
90%
science Other reagents with same CAS 128651-50-3
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description Product Description
This compound is a specialized trifluoromethanesulfonate (triflate) ester, functioning as a highly reactive electrophilic intermediate in organic synthesis. The triflate moiety serves as an excellent leaving group, facilitating nucleophilic substitutions and cross-coupling reactions such as Suzuki, Heck, or Sonogashira couplings to form carbon-carbon or carbon-heteroatom bonds. It is particularly valuable in pharmaceutical development for incorporating the 2-(1,3-dioxobenzo[f]isoindolin-2-yl)ethyl group into bioactive molecules, often as a protected form of an ethanolamine derivative. Applications extend to the synthesis of complex natural products, polymers, and other specialty chemicals where precise control over reactivity is required. Its use in medicinal chemistry aids in creating compounds with enhanced therapeutic potential, such as enzyme inhibitors or receptor agonists.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Off-White Solid, Powder, or Crystals |
| Purity | 89.5-100 |
| Proton NMR Spectrum | Conforms to Structure |
| Infrared Spectrum | Conforms to Structure |
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