Used primarily as an alkylating agent in organic synthesis, enabling the introduction of the but-3-yn-1-yl group to various nucleophiles. Its triflate functionality makes it highly reactive in palladium-catalyzed cross-coupling reactions, such as Sonogashira and Heck couplings, facilitating the construction of complex molecular architectures. Commonly employed in the synthesis of conjugated enynes and natural products, it serves as a versatile building block in pharmaceutical and agrochemical research. Due to the terminal alkyne moiety, it also supports click chemistry applications through copper-catalyzed azide-alkyne cycloaddition (CuAAC) after functionalization.