1-(((2R,3S)-2-(2,5-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
97%
Reagent
Code: #231338
CAS Number
241479-73-2
blur_circular Chemical Specifications
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Molecular Information
Weight
251.23 g/mol
Formula
C₁₂H₁₁F₂N₃O
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of antifungal agents, particularly in the development of triazole-based pharmaceuticals. It plays a critical role in inhibiting fungal lanosterol 14α-demethylase, an enzyme essential for ergosterol biosynthesis in fungal cell membranes. Due to its stereochemistry and functional groups, it enhances drug potency and selectivity, making it valuable in creating systemic antifungals for treating infections like candidiasis and aspergillosis. Its structure allows for optimization of pharmacokinetic properties such as bioavailability and metabolic stability in final drug formulations.
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