BAY-876 is primarily utilized in research settings, particularly in the study of cancer biology. It is a potent and selective inhibitor of the glucose transporter GLUT1, which plays a critical role in cancer cell metabolism. By inhibiting GLUT1, BAY-876 helps researchers understand the mechanisms of glucose uptake in cancer cells and its impact on tumor growth and survival. This makes it a valuable tool for investigating potential therapeutic strategies targeting metabolic pathways in cancer. Additionally, it aids in exploring the relationship between glucose metabolism and drug resistance in various cancer types. Its application extends to preclinical studies aimed at developing novel treatments for cancers that rely heavily on glucose for energy.