EIPA is primarily used in biological research as a selective inhibitor of the sodium-hydrogen exchanger (NHE) protein, particularly NHE1. It is employed to study the role of NHE1 in cellular processes such as pH regulation, cell volume control, and cell proliferation. In cancer research, EIPA helps investigate the involvement of NHE1 in tumor growth and metastasis, as its activity is often upregulated in cancer cells. Additionally, EIPA is utilized in cardiovascular studies to explore its effects on heart muscle cells and its potential role in ischemia-reperfusion injury. Its ability to modulate ion transport makes it a valuable tool in understanding cellular mechanisms and developing therapeutic strategies.