this item Can be sold only to hospitals, clinics, drug factories, pharmacists, doctors for use in research only. The purchaser must submit the following documents: Natural Person: Medical certificate or pharmacist Juristic Person: Documents received around the drug manufacturing site or a document certifying the hospital (clinic/hospital)
Cetirizine dihydrochloride recently found to have good efficacy in reducing hair loss
Pharmaceutical sciences branch, Islamic Azad University, Tehran, Iran;2Center for Research & Training in Skin Diseases & Leprosy, Tehran University ofMedical Sciences, Tehran, Iran.; 3Department of Pharmaceutics, Faculty of Pharmacy,Tehran University of Medical Sciences, Tehran, Iran;4Legacy Healthcare SA, Epalinges, Switzerland
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Study Purpose: Cetirizine, an antihistamine, is hypothesized to benefit hair growth by inhibiting prostaglandin D2 (which promotes hair loss) and stimulating prostaglandin E2 (which promotes hair growth). The study aimed to evaluate the effectiveness and safety of cetirizine for AGA compared to minoxidil, a well-established hair growth treatment.
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Methodology:
- Participants: 40 men with AGA were divided into two groups, each using either cetirizine 1% or minoxidil 5% for 16 weeks, followed by 8 weeks of placebo.
- Assessment: Hair density, diameter, and phases (anagen and telogen) were measured at the start, after 16 weeks, and again after the placebo period.
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Results:
- Hair Density: Both cetirizine and minoxidil significantly increased hair density, though minoxidil showed a more substantial effect.
- Hair Phases: An increase in hair in the anagen phase (growth phase) was observed in both groups, though it slightly decreased after the placebo.
- Patient and Physician Feedback: Patients and physicians noted improvements in hair density with both treatments, with minoxidil yielding higher satisfaction scores initially. However, cetirizine was found to maintain some effects even after stopping, indicating potential for longer-term use.
- Safety: Cetirizine had fewer side effects compared to minoxidil, which caused mild pruritus and scaling in some cases.
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Conclusion: Cetirizine 1% is effective for AGA treatment and may offer a safer alternative for those who experience side effects from minoxidil. Further research with larger samples and varied concentrations could provide more insights.
Use: use in medicine only Not allowed to use in cosmetics
Product characteristics: White powder, soluble in water.
Storage: For long term storage keep in refrigerator Do not expose to sunlight, heat, seal the lid tightly, shelf life at least 2 years.
Chemical Name : Cetirizine dihydrochloride
