Resatorvid is primarily used in research settings as a selective inhibitor of Toll-like receptor 4 (TLR4). It is widely studied for its potential to modulate inflammatory responses, making it a valuable tool in understanding conditions like sepsis, neuroinflammation, and other TLR4-mediated diseases. In preclinical studies, it has shown promise in reducing inflammation and improving outcomes in models of stroke, myocardial infarction, and chronic pain. Additionally, Resatorvid is explored for its role in cancer research, particularly in investigating how TLR4 signaling influences tumor progression and immune responses. Its application extends to studying the mechanisms of innate immunity and developing therapeutic strategies for inflammatory and autoimmune disorders.