Phenyltin trichloride is primarily used as a catalyst in the production of silicone polymers, facilitating cross-linking and curing processes through hydrosilylation reactions. It is also employed in organic synthesis for tin-mediated coupling reactions, such as Stille couplings. The compound exhibits biocidal properties, making it suitable as a preservative in industrial coatings, adhesives, and polymers to inhibit microbial growth and degradation. Additionally, it serves as an intermediate in the synthesis of other organotin compounds for applications in materials science, electronics, and advanced polymers. Limited research applications include preparing organotin derivatives with tailored electronic or structural properties. Due to its toxicity and potential environmental impact, handling requires strict safety precautions, including proper ventilation and protective equipment.