4-((Tetrahydro-2H-pyran-2-yl)methoxy)benzoic acid
97%
Reagent
Code: #46055
CAS Number
1020999-22-7
blur_circular Chemical Specifications
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Molecular Information
Weight
236.2637 g/mol
Formula
C₁₃H₁₆O₄
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Registry Numbers
MDL Number
MFCD11156613
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Storage & Handling
Storage
room temperature
description Product Description
This compound serves as a key intermediate in organic synthesis, particularly within the pharmaceutical industry for constructing complex molecules and active pharmaceutical ingredients (APIs). The tetrahydropyranyl (THP) moiety protects the hydroxymethyl group attached to the benzoic acid core, enabling selective functionalization of the carboxylic acid during multi-step reactions. It is also utilized in the synthesis of fine chemicals, esters, and amides, owing to the stability of the THP protecting group under basic and neutral conditions. Deprotection occurs readily under mild acidic conditions, restoring the free hydroxyl group.
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