2-(6-Bromohexyloxy)tetrahydro-2H-pyran
95%
Reagent
Code: #41800
CAS Number
53963-10-3
blur_circular Chemical Specifications
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Molecular Information
Weight
265.1872 g/mol
Formula
C₁₁H₂₁BrO₂
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Registry Numbers
MDL Number
MFCD00057971
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Storage & Handling
Storage
2-8°C
description Product Description
2-(6-Bromohexyloxy)tetrahydro-2H-pyran is the tetrahydropyranyl (THP) protected form of 6-bromohexan-1-ol. It functions as a synthetic intermediate in organic synthesis, where the THP group protects the hydroxyl functionality during reactions at the primary bromide terminus. The bromide enables alkylation, nucleophilic substitutions, or other functionalizations, after which the THP group is selectively removed under mild acidic conditions to reveal the free alcohol. This reagent is essential for installing a 6-hydroxyhexyl chain in pharmaceuticals, natural products, and fine chemicals, offering orthogonality in multi-step syntheses requiring selective protection/deprotection.
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