1-[3,5-Bis(trifluoromethyl)phenyl]-3-[(1R,2R)-2-(dimethylamino)cyclohexyl]thiourea
≥98%,99%e.e.
science Other reagents with same CAS 620960-26-1
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description Product Description
This chiral thiourea compound serves as a highly effective organocatalyst in asymmetric synthesis, particularly for enantioselective additions and cycloadditions. Its structure, incorporating a 3,5-bis(trifluoromethyl)phenyl group and a (1R,2R)-2-(dimethylamino)cyclohexyl moiety, enables strong hydrogen-bond donation to activate substrates like imines, promoting stereocontrolled reactions with high enantioselectivity. It is extensively used in the preparation of enantiomerically pure intermediates for pharmaceuticals, agrochemicals, and fine chemicals. While it may have applications in medicinal chemistry research as a modulator of biological targets, its primary role is in synthetic organic chemistry to enhance reaction efficiency and selectivity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white solid |
| Purity | 97.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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