1-[(1R,2R)-2-(Dimethylamino)cyclohexyl]-3-(perfluorophenyl)thiourea
≥98%,≥99%e.e.
Reagent
Code: #70580
blur_circular Chemical Specifications
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Molecular Information
Weight
367.4 g/mol
Formula
C₁₅H₁₈F₅N₃S
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Storage & Handling
Storage
room temperature, dry
description Product Description
This chiral thiourea derivative is primarily employed as an organocatalyst in asymmetric organic synthesis within medicinal and pharmaceutical chemistry. Featuring a (1R,2R)-2-(dimethylamino)cyclohexyl moiety and a perfluorophenyl group, it facilitates stereoselective reactions through hydrogen bonding and Brønsted acidity, enabling the efficient construction of complex molecular architectures with high enantioselectivity. It is particularly valuable for accelerating reactions and controlling stereochemistry in the synthesis of biologically active compounds, including potential drug candidates. The fluorinated aromatic group enhances the catalyst's potency, stability, and solubility in various solvents, making it a key tool in the development of novel therapeutics for diseases such as cancer and neurological disorders.
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