(S)-1-(3,5-Bis(trifluoromethyl)phenyl)-3-(1-(dimethylamino)-3-methylbutan-2-yl)thiourea
98%
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This chiral thiourea is primarily employed as an organocatalyst in asymmetric organic synthesis and pharmaceutical research. It excels in facilitating stereoselective reactions, particularly those involving carbon-nitrogen bond formation and the construction of complex, enantiomerically enriched molecular structures. The distinctive features, including the 3,5-bis(trifluoromethyl)phenyl group and the chiral 1-(dimethylamino)-3-methylbutan-2-yl substituent, enable effective hydrogen-bond donor activation of substrates, promoting high levels of enantioselectivity. This makes it invaluable for developing potent enzyme inhibitors and biologically active compounds with applications in antiviral and anticancer therapies. Additionally, its role extends to studying reaction mechanisms and optimizing synthetic routes for enantiomerically pure pharmaceuticals in laboratory environments.
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