Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its strong hydrogen-bonding capability makes it valuable in supramolecular chemistry and anion recognition systems. Also employed in agrochemical research for designing novel pesticides due to the stability and electron-withdrawing nature of the trifluoromethyl groups. Shows utility in materials science for constructing functional organic frameworks with enhanced thermal and chemical resistance. Additionally, it serves as a ligand in coordination chemistry to form transition metal complexes with special properties for catalysis or chemical sensing.