Used as a building block in pharmaceutical synthesis, particularly in the development of enzyme inhibitors and bioactive molecules. Its rigid, polar structure makes it valuable for modifying peptide-like compounds to enhance metabolic stability and binding selectivity. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to mimic amino acid motifs while improving pharmacokinetic properties. Also utilized in the design of protease inhibitors and central nervous system (CNS) agents where conformational restraint is beneficial.