Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of targeted therapies where iodinated thiophene derivatives play a role in enhancing binding selectivity. Its alkyne functionality allows for further modification via click chemistry, making it valuable in medicinal chemistry for building complex molecules. Also employed in research settings to prepare radiolabeled compounds for imaging studies, leveraging the iodine atom for incorporation of radioactive isotopes. The carboxylic acid group enables conjugation to carriers or solid supports, useful in assay development and drug delivery systems.