Used as a key intermediate in organic synthesis, particularly in the construction of nitrogen-containing heterocycles. It participates in [3+2] cycloaddition reactions with alkynes or alkenes to produce imidazoles or pyrroles. Its isocyano group also participates in multicomponent reactions, such as Ugi or Passerini reactions, enabling efficient assembly of complex molecules for pharmaceutical and agrochemical research. The tosyl group enhances stability and directs regioselectivity during transformations. It is especially valuable in drug discovery for generating diverse compound libraries and in the development of bioactive molecules, such as antimicrobials or enzyme inhibitors, due to its versatility in forming carbon–carbon and carbon–nitrogen bonds.