Cyclobutylmethanethiol is primarily used in organic synthesis as a building block for more complex chemical structures. Its thiol group makes it a valuable reagent for introducing sulfur-containing functional groups into molecules, which is essential in the development of pharmaceuticals and agrochemicals. Additionally, it can be employed in the creation of ligands for metal catalysis, enhancing the efficiency of various chemical reactions. The compound’s unique cyclobutyl ring also contributes to its utility in the design of novel materials with specific properties, such as increased rigidity or stability. In research, it serves as a precursor for studying reaction mechanisms involving sulfur compounds, aiding in the advancement of synthetic methodologies.