Cyclohexanethione is primarily used as a reagent and intermediate in organic synthesis. Its reactive thiocarbonyl group makes it valuable in the formation of heterocyclic compounds and sulfur-containing molecules. It participates in cycloaddition reactions, including [4+2] Diels-Alder reactions, enabling the construction of complex ring systems found in pharmaceuticals and agrochemicals. It is also employed in studies involving thioketone chemistry, helping to explore reaction mechanisms and electronic properties of thio-carbonyl compounds. Due to its ability to act as a sulfur transfer agent, it has potential use in the development of new synthetic routes for sulfur-functionalized organic materials.