Used primarily in the treatment of type 2 diabetes, it functions as an insulin sensitizer by activating peroxisome proliferator-activated receptor gamma (PPAR-γ). This activation helps regulate blood sugar levels by improving insulin sensitivity in adipose tissue, muscle, and the liver. It is often prescribed when other medications, such as metformin or sulfonylureas, are not sufficient to control blood glucose levels. Additionally, it may be used in combination with other antidiabetic agents to enhance glycemic control. Its use requires careful monitoring due to potential side effects, including weight gain and cardiovascular risks.