tert-Butyl (2-bromo-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)carbamate
≥95%
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description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure allows for selective modification in heterocyclic compounds, making it valuable in creating potent and selective kinase inhibitors. Commonly employed in medicinal chemistry for constructing constrained peptidomimetics due to the rigid thiazole ring fused with a cyclohexene framework. The tert-butyl carbamate (Boc) group serves as a protecting group for amines, enabling controlled deprotection during multi-step syntheses. Also utilized in the preparation of receptor agonists and antagonists, especially in serotonin and dopamine receptor research. Its bromo functionality provides a site for cross-coupling reactions, facilitating the introduction of aryl or heteroaryl groups via palladium-catalyzed transformations.
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