tert-Butyl (2-bromo-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)carbamate

≥95%

Reagent Code: #148187
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CAS Number 1251009-79-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 333.25 g/mol
Formula C₁₂H₁₇BrN₂O₂S
badge Registry Numbers
MDL Number MFCD13195380
thermostat Physical Properties
Boiling Point 432.5±34.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, stored in inert gas

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure allows for selective modification in heterocyclic compounds, making it valuable in creating potent and selective kinase inhibitors. Commonly employed in medicinal chemistry for constructing constrained peptidomimetics due to the rigid thiazole ring fused with a cyclohexene framework. The tert-butyl carbamate (Boc) group serves as a protecting group for amines, enabling controlled deprotection during multi-step syntheses. Also utilized in the preparation of receptor agonists and antagonists, especially in serotonin and dopamine receptor research. Its bromo functionality provides a site for cross-coupling reactions, facilitating the introduction of aryl or heteroaryl groups via palladium-catalyzed transformations.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,070.00
inventory 250mg
10-20 days ฿5,140.00
inventory 1g
10-20 days ฿19,600.00

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