2-Chloro-5-methyl-1,3,4-thiadiazole is primarily used as a key intermediate in the synthesis of various agrochemicals, particularly herbicides and fungicides that target and control unwanted plant growth and fungal infections in crops. It also serves as a building block in the development of pharmaceuticals with potential antimicrobial and anti-inflammatory properties. In research, it is utilized to explore novel chemical reactions and synthetic pathways in organic chemistry.