5-(3-Bromo-4-methylphenyl)-2H-tetrazole
95%
Reagent
Code: #153277
CAS Number
326912-89-4
blur_circular Chemical Specifications
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as candesartan and valsartan. Its bromo and tetrazole functionalities allow for selective cross-coupling reactions and enhance binding affinity to the AT1 receptor. Commonly employed in pharmaceutical research and development for optimizing drug candidates targeting hypertension and cardiovascular diseases. Also utilized in medicinal chemistry for building biologically active heterocyclic compounds due to the metabolic stability and polarity provided by the tetrazole ring.
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