Tetrahydrofuran-3-carbonyl chloride is primarily used as a versatile intermediate in organic synthesis. It plays a key role in the production of pharmaceuticals, where it is employed in the formation of complex molecules through reactions such as acylation and esterification. Its reactive carbonyl chloride group makes it valuable for coupling with amines, alcohols, and other nucleophiles to generate amides, esters, and other derivatives. Additionally, it is utilized in the development of agrochemicals and specialty chemicals, contributing to the synthesis of compounds with specific biological activities. Its application in polymer chemistry is also notable, where it aids in the modification of polymers to enhance their properties. Overall, it is a crucial building block in the fine chemical and material science industries.