Sodium malonate dibasic monohydrate is widely used in organic synthesis as a reagent for the preparation of various chemical compounds. It serves as a key intermediate in the production of pharmaceuticals, particularly in the synthesis of barbiturates and other heterocyclic compounds. In biochemistry, it is utilized as a competitive inhibitor of succinate dehydrogenase, making it valuable in enzymatic studies and metabolic pathway investigations. Additionally, it finds application in the manufacturing of dyes, pigments, and coatings due to its role as a precursor in chemical reactions. Its buffering properties also make it suitable for use in laboratory settings for maintaining pH stability in biochemical experiments.