3-Nitropropionic acid
95%
Reagent
Code: #216704
Alias
3-Nitropropionic acid
CAS Number
504-88-1
blur_circular Chemical Specifications
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Molecular Information
Weight
119.08 g/mol
Formula
C₃H₅NO₄
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Registry Numbers
EC Number
208-003-0
MDL Number
MFCD00007406
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Physical Properties
Melting Point
68-70 °C(lit.)
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a potent neurotoxin in scientific research to model neurodegenerative diseases such as Huntington's disease. It induces selective damage to the striatum in the brain by inhibiting mitochondrial succinate dehydrogenase, leading to energy depletion and neuronal cell death. This makes it valuable in studying mechanisms of oxidative stress, excitotoxicity, and potential neuroprotective therapies. Also investigated for its role in understanding stroke and Parkinsonian symptoms in animal models. Due to its high toxicity, it is handled with strict safety controls and not used in industrial or commercial applications outside research settings.
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