Used as a chiral ligand in asymmetric catalysis, particularly in the Sharpless asymmetric epoxidation of allylic alcohols and the Sharpless asymmetric dihydroxylation of olefins, where it complexes with titanium or osmium catalysts to achieve high enantioselectivity. The bulky tert-butyl groups provide essential steric control for stereodifferentiation. It also functions as a chiral auxiliary in enantioselective aldol and alkylation reactions. Commonly employed in pharmaceutical synthesis to construct chiral centers in complex molecules and in the preparation of optically active intermediates for natural products and bioactive compounds. Stable under a variety of reaction conditions, making it suitable for multi-step synthetic routes.