Used in radiopharmaceutical development for targeted cancer imaging and therapy. The nitro group enhances binding selectivity when conjugated to targeting vectors like peptides or antibodies. Serves as a chelator for radiometals such as gallium-68, lutetium-177, or yttrium-90 in PET imaging and radiotherapy. Commonly applied in preclinical studies for tumor localization due to its stability and efficient metal coordination. The p-NO2-Bn group improves lipophilicity and cell permeability, aiding in in vivo distribution and uptake.