2-(2,6-dioxopiperidin-3-yl)-4-hydroxyisoindoline-1,3-dione

95%

Reagent Code: #64507
fingerprint
CAS Number 5054-59-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 274.23 g/mol
Formula C₁₃H₁₀N₂O₅
thermostat Physical Properties
Melting Point 273-275 °C
Boiling Point 568.3±45.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.611±0.06 g/cm3(Predicted)
Storage 2-8℃

description Product Description

This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific disease-causing proteins within cells. Its structure allows it to bind effectively to E3 ubiquitin ligase, facilitating the tagging and subsequent degradation of target proteins. This mechanism is especially valuable in treating cancers driven by proteins that are traditionally difficult to inhibit with conventional drugs. Additionally, it is explored in research for its potential in treating neurodegenerative diseases by targeting misfolded proteins. Its application extends to the study of protein-protein interactions and cellular pathways, providing insights into disease mechanisms and therapeutic strategies.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance white to yellow to light purple to gray solid
Purity 94.5-100
NMR Conforms to Structure
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100g
10-20 days ฿75,840.00
inventory 5g
10-20 days ฿4,640.00
inventory 100mg
10-20 days ฿380.00
inventory 1g
10-20 days ฿1,090.00
inventory 10g
10-20 days ฿8,500.00
inventory 25g
10-20 days ฿19,070.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB