PROTAC CRABP-II Degrader-1 is primarily utilized in the field of targeted protein degradation, specifically for research purposes. It functions by inducing the degradation of cellular retinoic acid-binding protein II (CRABP-II), which plays a role in retinoic acid signaling pathways. This compound is particularly valuable in studying the effects of CRABP-II loss in cellular processes, including differentiation, proliferation, and apoptosis. Researchers employ it to explore potential therapeutic strategies for diseases where CRABP-II is implicated, such as certain cancers or metabolic disorders. Its ability to selectively degrade the target protein makes it a powerful tool for understanding protein function and validating drug targets in preclinical studies.