N-((1R,4R)-4-(3-Chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2,6-dioxopiperidin-3-yl)-6-fluoro-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide

97%

Reagent Code: #55965
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CAS Number 2222112-77-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 812.29 g/mol
Formula C₄₁H₄₃ClFN₉O₆
inventory_2 Storage & Handling
Storage 2-8 ℃, inert gas storage

description Product Description

This compound is primarily utilized in the field of targeted protein degradation, particularly in the development of proteolysis-targeting chimeras (PROTACs). It functions by recruiting specific proteins to E3 ubiquitin ligases, leading to their ubiquitination and subsequent degradation by the proteasome. This mechanism is especially valuable in cancer research, where it helps degrade oncogenic proteins that are otherwise difficult to target with traditional small-molecule inhibitors. Its structure includes a ligand for E3 ligase and a moiety that binds to the target protein, making it a versatile tool for studying disease-related proteins and developing potential therapeutic strategies. Additionally, its application extends to probing biological pathways and understanding protein function in cellular contexts.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance Light yellow to yellow Solid
Purity (%) 96.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿8,982.00
inventory 25mg
10-20 days ฿26,964.00

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