PROTAC Bcl2 degrader-1
98%
Reagent
Code: #55747
CAS Number
2378801-85-3
blur_circular Chemical Specifications
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Molecular Information
Weight
941.84 g/mol
Formula
C₄₅H₄₅BrN₆O₁₀S
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Storage & Handling
Storage
-20°C
description Product Description
This compound is primarily used in the field of cancer research and therapy. It functions as a Proteolysis Targeting Chimera (PROTAC) designed to target and degrade Bcl-2, a protein that plays a critical role in preventing apoptosis in cancer cells. By degrading Bcl-2, it promotes programmed cell death in malignant cells, making it a promising tool for developing treatments for Bcl-2-dependent cancers such as certain types of leukemia and lymphoma. Its application is particularly significant in overcoming resistance to traditional Bcl-2 inhibitors, offering a novel approach to cancer therapy. Research is ongoing to evaluate its efficacy, specificity, and potential for clinical use.
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