PROTAC BRD4 Degrader-10
98%
Reagent
Code: #55724
CAS Number
2417370-49-9
blur_circular Chemical Specifications
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Molecular Information
Weight
1312.50 g/mol
Formula
C₅₉H₇₁F₂N₉O₁₅S₄
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Storage & Handling
Storage
2-8°C
description Product Description
PROTAC BRD4 Degrader-10 is primarily used in biomedical research to target and degrade the BRD4 protein, which plays a critical role in regulating gene expression and is often implicated in various cancers. By leveraging the PROTAC (Proteolysis Targeting Chimera) technology, this compound facilitates the recruitment of E3 ubiquitin ligase to BRD4, marking it for proteasomal degradation. This approach is particularly valuable in studying cancer biology, as it helps to elucidate the role of BRD4 in tumor growth and progression. Additionally, it serves as a potential therapeutic strategy for diseases where BRD4 overexpression is a contributing factor, such as certain types of leukemia and solid tumors. Its application extends to drug discovery, where it aids in validating BRD4 as a therapeutic target and in developing novel treatments.
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