(S,R,S)-AHPC-phenol-C4-NH2 dihydrochloride
≥95%
Reagent
Code: #106532
CAS Number
2376990-26-8
blur_circular Chemical Specifications
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Molecular Information
Weight
632.64 g/mol
Formula
C₂₈H₄₃Cl₂N₅O₅S
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Storage & Handling
Storage
-20°C, dry, sealed
description Product Description
This compound is primarily utilized in the field of biomedical research, particularly in the study of protein degradation and targeted protein knockdown. It serves as a key component in the development of Proteolysis Targeting Chimeras (PROTACs), which are innovative molecules designed to selectively degrade specific proteins within cells. By facilitating the recruitment of E3 ubiquitin ligases to target proteins, it enables their ubiquitination and subsequent degradation by the proteasome. This mechanism is highly valuable in exploring disease-related proteins, especially in cancer research, where it aids in understanding and potentially inhibiting the function of oncogenic proteins. Additionally, it is used in chemical biology to investigate cellular pathways and protein functions, providing insights into therapeutic target discovery and drug development.
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