2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione

97%

Reagent Code: #73986
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CAS Number 19171-18-7

science Other reagents with same CAS 19171-18-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 303.23 g/mol
Formula C₁₃H₉N₃O₆
badge Registry Numbers
MDL Number MFCD01748356
thermostat Physical Properties
Boiling Point 603.4°C at 760 mmHg
inventory_2 Storage & Handling
Storage room temperature, stored under inert gas

description Product Description

This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific proteins involved in cancer progression. By binding to both the target protein and an E3 ubiquitin ligase, it facilitates the ubiquitination and subsequent degradation of the protein, offering a novel approach to cancer treatment. Additionally, it has been explored for its potential in treating neurodegenerative diseases by targeting misfolded proteins. Its unique structure allows for selective interaction with disease-related proteins, making it a valuable tool in drug discovery and therapeutic development.

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Test Parameter Specification
Appearance Off-White to Gray to Yellowish Grey Solid
Purity (%) 96.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿270.00
inventory 250mg
10-20 days ฿351.00
inventory 1g
10-20 days ฿783.00
inventory 5g
10-20 days ฿2,763.00

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2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
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This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific proteins involved in cancer progression. By binding to both the target protein and an E3 ubiquitin ligase, it facilitates the ubiquitination and subsequent degradation of the protein, offering a novel approach to cancer treatment. Additionally, it has been e

This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in proteolysis-targeting chimeras (PROTACs), which are designed to degrade specific proteins involved in cancer progression. By binding to both the target protein and an E3 ubiquitin ligase, it facilitates the ubiquitination and subsequent degradation of the protein, offering a novel approach to cancer treatment. Additionally, it has been explored for its potential in treating neurodegenerative diseases by targeting misfolded proteins. Its unique structure allows for selective interaction with disease-related proteins, making it a valuable tool in drug discovery and therapeutic development.

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