JWH 081 2-methoxynaphthyl isomer, also known as JWH 267, is primarily utilized in research settings to study cannabinoid receptor interactions. Its application is focused on understanding the pharmacological effects and binding mechanisms of synthetic cannabinoids on CB1 and CB2 receptors. Researchers use it to explore the structure-activity relationship (SAR) of cannabinoid compounds, which helps in developing insights into potential therapeutic applications or identifying risks associated with synthetic cannabinoid use. It is not intended for human or animal consumption and is strictly confined to controlled laboratory environments for scientific investigation.