RCS-8 3-methoxy isomer is primarily utilized in research settings to study its interaction with cannabinoid receptors, particularly CB1 and CB2. Its structural properties make it a valuable tool for investigating the pharmacological effects of synthetic cannabinoids. Researchers use it to explore receptor binding affinity, signaling pathways, and potential physiological responses. Additionally, it aids in understanding the structure-activity relationship of synthetic cannabinoids, contributing to the development of more targeted therapeutic agents or the identification of potential risks associated with synthetic cannabinoid use.