Bis(2-methoxyethyl) sulfate is primarily used as an intermediate in the synthesis of various chemical compounds. It plays a significant role in the production of specialty chemicals, particularly in the development of surfactants and emulsifiers. These surfactants are then utilized in the formulation of industrial cleaning agents, detergents, and personal care products, where they help to reduce surface tension and improve the mixing of oil and water.

In addition, it is employed in the manufacturing of polymers and coatings, where it acts as a reactive monomer or cross-linking agent. This contributes to the enhancement of the durability, flexibility, and adhesion properties of the final polymer products. Its application in the electronics industry is also notable, where it is used in the production of electrolytes for batteries and other electronic components, aiding in the efficient conduction of ions.

Furthermore, bis(2-methoxyethyl) sulfate is sometimes used in laboratory settings as a reagent for organic synthesis, facilitating the creation of complex molecules for research and development purposes. Its versatility and reactivity make it a valuable component in various industrial and scientific applications.