Used in bioconjugation processes to modify peptides, proteins, and nanoparticles, enhancing water solubility and reducing immunogenicity. Its PEG spacer improves stability and bioavailability of conjugated molecules, making it valuable in drug delivery systems and therapeutic development. Commonly employed in the synthesis of antibody-drug conjugates (ADCs) and diagnostic probes due to its biocompatibility and ability to extend circulation half-life. Also utilized in surface functionalization of materials for biosensors and medical devices.