N-Boc-2-Amino-4-formylthiazole
98%
Reagent
Code: #217366
CAS Number
494769-34-5
science Other reagents with same CAS 494769-34-5
blur_circular Chemical Specifications
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Molecular Information
Weight
228.27 g/mol
Formula
C₉H₁₂N₂O₃S
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Storage & Handling
Storage
2-8°C, inert gas atmosphere
description Product Description
Used as a key intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical development. Its aldehyde group allows for further functionalization via reactions such as reductive amination or Wittig reactions, enabling the construction of complex heterocyclic systems. The Boc-protected amine ensures stability during multi-step syntheses and can be deprotected under mild acidic conditions to release the free amine for subsequent coupling steps. Commonly employed in the preparation of kinase inhibitors and other drug candidates where the thiazole core is essential for activity. Its structural features make it valuable in combinatorial chemistry and medicinal chemistry research for generating diverse compound libraries.
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