Ethyl 2-(2-aminothiazol-4-yl)glyoxylate
98%
Reagent
Code: #182169
Alias
Aminothiazole ethyl glycoloxylate; 2-(2-aminothiazole-4-yl)glyoxylate; 2-amino-4-thiazole ethyl glycoloxylate; ethyl 2-(2-aminothiazole-4-yl)glyoxylate; 2-(2-amino-4-thiazole)-2-oxoacetate
CAS Number
64987-08-2
blur_circular Chemical Specifications
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Molecular Information
Weight
200.22 g/mol
Formula
C₇H₈N₂O₃S
thermostat
Physical Properties
Melting Point
150-152 °C
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Storage & Handling
Storage
Room temperature
description Product Description
Widely used as a key intermediate in the synthesis of β-lactam antibiotics, particularly cephalosporins. It plays a critical role in constructing the core structure of these antibiotics by enabling the introduction of the aminothiazole ring, which enhances antimicrobial activity and improves pharmacokinetic properties. Its reactivity allows for efficient coupling with various side chains, making it valuable in pharmaceutical research and development for creating semi-synthetic antibiotics. Commonly employed in multi-step organic syntheses where selective functional group transformations are required.
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