Used primarily as a specialty reagent in organic synthesis, particularly in the introduction of the pentafluorosulfanyl (SF5) group into aromatic systems. The SF5 group is valued for its strong electron-withdrawing properties, high lipophilicity, and metabolic stability, making it useful in the development of pharmaceuticals and agrochemicals. This compound serves as a building block for creating novel fluorinated molecules with enhanced biological activity and improved pharmacokinetic profiles. It is also employed in materials science for designing high-performance liquid crystals and energetic materials due to the thermal and oxidative stability imparted by the SF5 moiety. Its application remains largely confined to research settings given the niche nature of pentafluorosulfanylated compounds.