Dodecane-1-sulfonyl chloride is primarily used as a reagent in organic synthesis, particularly in the preparation of sulfonamides. It acts as a sulfonating agent, enabling the introduction of the sulfonyl group into various organic compounds. This chemical is valuable in the pharmaceutical industry for creating intermediates in drug development, especially for antibiotics and other therapeutic agents. Additionally, it finds application in the production of surfactants and detergents, where its sulfonyl group enhances the properties of these materials. Its role in modifying polymers and coatings also makes it useful in material science, improving durability and performance.