Widely used in organic synthesis as a sulfonylating agent, particularly in the preparation of sulfonamides, which are key motifs in pharmaceuticals and agrochemicals. Its electron-withdrawing nitro and trifluoromethyl groups enhance reactivity and stability of intermediates. Commonly employed in the development of bioactive molecules, including protease inhibitors and antimicrobial agents. Also serves as a building block in the synthesis of dyes and functional materials due to its robust electrophilic character.