3-Fluoro-4-nitrobenzene-1-sulfonyl chloride
95%
Reagent
Code: #188429
CAS Number
86156-93-6
blur_circular Chemical Specifications
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Molecular Information
Weight
239.61 g/mol
Formula
C₆H₃ClFNO₄S
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Registry Numbers
MDL Number
MFCD03412240
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Physical Properties
Melting Point
44-48 °C
Boiling Point
418.6 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, inert gas storage
description Product Description
Used primarily as an intermediate in organic synthesis, especially in the pharmaceutical and agrochemical industries. Its structure allows for selective functionalization, making it valuable in constructing complex molecules. The sulfonyl chloride group readily reacts with amines and alcohols to form sulfonamides and sulfonate esters, which are key motifs in drug design. The presence of both fluoro and nitro groups enhances its reactivity and provides sites for further transformation, such as nucleophilic aromatic substitution or reduction of the nitro group. Commonly employed in the development of sulfonamide-based bioactive compounds and as a building block in medicinal chemistry research.
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