Widely used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the preparation of herbicides and fungicides. Its reactive sulfonyl chloride group enables easy derivatization to form sulfonamides, which are common structural motifs in bioactive molecules. It is also employed in organic synthesis for introducing the 2,6-dichloro-3-nitrobenzenesulfonyl (Dns) protecting group, especially for amines, due to its stability and selective deprotection properties. The electron-withdrawing chloro and nitro groups enhance its reactivity in nucleophilic substitution reactions, making it valuable in the development of complex organic compounds.